paaT — Aspergillus nidulans FGSC A4

Summary

ANIA_02841 (paaT) on chromosome 6 of Aspergillus nidulans FGSC A4 encodes a major facilitator superfamily (MFS) domain-containing protein with xenobiotic transmembrane transporter activity. The gene is associated with transport of peptides, fluconazole, spermidine, and hexoses, as well as penicillin anabolism, pexophagy, secretion, and cellular responses to xenobiotic stimuli. Its product localizes to the peroxisome membrane, plasma membrane, and general membrane compartments. Studies of related genes in other species link the family to reduced virulence and candidiasis.