sltA — Aspergillus nidulans FGSC A4

Summary

ANIA_02919 (sltA) on chromosome 6 of Aspergillus nidulans encodes a C2H2-type domain-containing protein with sequence-specific DNA binding and RNA polymerase II transcription factor activity, localised to the nucleus. The gene is associated with monoatomic cation homeostasis, cellular responses to potassium and calcium ions, cell volume homeostasis, and salinity response. It is also linked to both asexual and sexual sporulation, appressorium formation, sterigmatocystin anabolism, vacuolar protein sorting, detoxification, morphogenesis, and signal transduction. Studies of related genes in other species link the family to reduced virulence, though this association is not established for sltA itself.