NSDD — Aspergillus nidulans FGSC A4

Summary

ANIA_03152 (NSDD, nsdD) on chromosome 6 of Aspergillus nidulans FGSC A4 encodes a GATA-type zinc-finger protein that binds DNA and cis-regulatory regions. This gene is associated with sclerotium development, cleistothecium development, conidiophore development, fruiting body formation, photomorphogenesis, positive regulation of sexual sporulation, asexual reproduction, appressorium formation, cell volume homeostasis, carbon catabolite repression, alternative respiration, pigment anabolism, penicillin anabolism, upregulation of biofilm formation, and upregulation of filamentous growth. The encoded product localises to chromatin and the nucleus. Studies of related genes in other species connect the family to altered virulence, including both hypervirulence and reduced virulence.