AGS1 — Aspergillus nidulans FGSC A4

Summary

AnAGS1 (ANIA_03307) on chromosome 6 encodes an alpha-1,3-glucan synthase, an enzyme with alpha-1,4-glucan glucosyltransferase (NDP-glucose donor) activity (EC 2.4.1.183). The gene is associated with alpha-glucan anabolism, specifically 1,3-alpha-glucan and fungal-type cell wall 1,3-alpha-glucan anabolism, as well as ascospore wall biogenesis, primary cell septum biogenesis, fungal-type cell wall biogenesis, melanin anabolism, and cell wall organization. Its product localizes to the ascus membrane, ascospore wall, external side of the plasma membrane, new and old growing cell tips, medial membrane band, division septum, and cell periphery. Studies of related genes in other species link the family to turgor pressure and germination rate.