prnB — Aspergillus nidulans FGSC A4

Summary

ANIA_03287 (prnB) on chromosome 6 of Aspergillus nidulans FGSC A4 encodes an amino acid transporter belonging to the APC_YAT family, with molecular functions including L-proline, L-histidine, L-arginine, L-lysine, and basic amino acid transmembrane transporter activity, as well as amino acid binding. The gene is associated with proline transport, import, metabolism, and breakdown, response to proline and amino acid starvation, carbon catabolite repression, depurination, amino acid import and membrane transport, basic amino acid transport, and single-species biofilm formation. Its product localizes to the plasma membrane, eisosome, fungal-type cell wall, Golgi complex, and endoplasmic reticulum. Studies of related genes in other species link the family to reduced virulence, though this is not established for prnB itself.