AMD2 — Aspergillus nidulans FGSC A4

Summary

AnAMD2 (ANIA_02829) on chromosome 6 of Aspergillus nidulans FGSC A4 encodes a protein with amidase, fatty acid amide hydrolase, and glutaminyl-tRNA synthase (glutamine-hydrolyzing) activities, and contains an amidase domain. The gene is associated with glutaminyl-tRNAGln biosynthesis via transamidation, mitochondrial translation, carbon catabolite repression, antibiotic anabolism, and fatty acid breakdown. Its product localises to the glutamyl-tRNA(Gln) amidotransferase complex, mitochondria, cytoplasm, cytosol, and nucleus. Related genes in other species are linked to glutamyl-tRNA(Gln) amidotransferase subunit A function and N-acylethanolamine amidohydrolase activity, as well as to altered starvation resistance and chemical sensitivity phenotypes.