MAT1 — Aspergillus nidulans FGSC A4

Summary

ANIA_02755 (MAT1) on chromosome 6 of Aspergillus nidulans FGSC A4 encodes a protein containing a MATalpha_HMGbox domain, which is associated with DNA binding and bending. The gene is linked to upregulation of transcription, mating-type specific, and is associated with both sexual and asexual reproduction, including cleistothecium development, ascospore formation, and sporulation. It has also been associated with secondary metabolism, anaphase, and single fertilization. The encoded product localizes to the nucleus. Studies of related genes in other species link the family to similar roles in reproduction and development.