CHS3 — Aspergillus nidulans FGSC A4

Summary

ANIA_01555 (CHS3, AnCHS3) on chromosome 7 encodes a chitin synthase with chitin synthase activity (EC 2.4.1.16), placing it in the chitin synthase family. The gene is associated with conidiophore development, asexual sporulation, ascospore wall assembly, hyphal growth, and chitin anabolism. It is linked to cellular mechanical stimulus response, protein localization to the bud neck, and fermentation. Localization evidence connects the product to the chitosome, cross wall, incipient cellular bud site, cellular bud neck, extracellular vesicle, and plasmalemma. Phenotypic associations include decreased septum formation, abnormal chitin deposition, abnormal spore wall formation, delayed G2 phase progression, increased alkaline pH resistance, and decreased adhesion. Related genes in other species link the family to polysaccharide content and salt tolerance traits.