pbcA — Aspergillus nidulans FGSC A4

Summary

ANIA_01594 (symbol pbcA) on chromosome 7 of Aspergillus nidulans FGSC A4 encodes a terpene synthase-like protein with ent-kaurene synthase, syn-copalyl diphosphate synthase, ent-copalyl diphosphate synthase, aphidicolan-16 beta-ol synthase, ent-pimara-8(14),15-diene synthase, copalyl diphosphate synthase, terpene synthase, farnesyltranstransferase, and isomerase activities, and binds magnesium and other metals. The gene is associated with terpene, diterpenoid, geranylgeranyl diphosphate, alcohol, isoprenoid, antibiotic, and mycotoxin anabolism, as well as gibberellin biosynthesis. Studies of related genes in other species link the family to additional terpene synthase activities, including EC 5.5.1.14, 4.2.3.45, 4.2.3.19, 4.2.3.42, 5.5.1.12, and 2.5.1.29.