ACUF — Aspergillus nidulans FGSC A4

Summary

The Aspergillus nidulans gene ACUF (ANIA_01918) on chromosome 7 encodes a phosphoenolpyruvate carboxykinase (ATP) (EC 4.1.1.49). The encoded protein contains PEP carboxykinase ATP and binds ATP. The gene is associated with gluconeogenesis, the glyoxylate cycle, carbon catabolite repression, alternative respiration, acetate metabolism, the TCA cycle, heterotrophy, detoxification, morphogenesis, and filamentous growth. It localizes to the cytosol and cell-bound compartments. Phenotypic associations include absent anaerobic and filamentous growth, increased resistance to hydrostatic pressure and alkaline pH, abnormal colony shape, septum formation, cell size, and budding pattern, normal chronological lifespan, increased entry into G0, decreased nutrient uptake and chemical compound excretion, and premature cell cycle progression in metaphase and telophase.