vosA — Aspergillus nidulans FGSC A4

Summary

ANIA_01959 (vosA) on chromosome 7 of Aspergillus nidulans FGSC A4 encodes a velvet domain-containing protein with identical protein binding. This gene is associated with the regulation of secondary metabolism, including the anabolism of PR-toxin, penicillin, carotenoids, and mycose. It is linked to both asexual and sexual sporulation, spore wall assembly, karyogamy, autolysis, chitin and glucan metabolism, and the osmotic stress response. The encoded protein localises to the cytoplasm and nucleus. Studies of related genes in other species link the family to reduced virulence and unaffected pathogenicity in diseases such as common root rot and spot blotch of barley and wheat, and blast of rice.