CP1 — Aspergillus nidulans FGSC A4

Summary

ANIA_02237 (CP1, AnCP1) on chromosome 7 encodes a serine carboxypeptidase (EC 3.4.16.6) belonging to the peptidase S10 family, with serine carboxypeptidase activity confirmed by annotation. The gene is associated with proteolysis, intracellular transport, regulation of gene expression, chromatin organization, methylation, homeostasis, and NO storage. The product localizes to the fungal-type vacuole, plasmalemma, and side of membrane. Phenotypic associations include altered cell death, autophagy, endocytosis, cytokinesis, nuclear fusion during mating, prion inheritance, replicative lifespan, protein secretion, and chemical compound accumulation. The gene is also linked to abnormal Golgi morphology, nuclear position, and increased aneuploidy. Studies of related genes in other species connect it to apoplastic effector functions and floral organ identity, though these are not established for this Aspergillus gene.