ADH1 — Aspergillus nidulans FGSC A4

Summary

AnADH1 (ANIA_02286) on chromosome 7 encodes an alcohol dehydrogenase (ADH3) with aldo-keto reductase (NAD) activity, belonging to the ADH_Zn_CS and PKS_ER domain families. It is associated with ethanol fermentation, acetaldehyde breakdown, ethanol breakdown, threonine breakdown, aflatoxin anabolism, cellular response to farnesol, and carbohydrate metabolism. The gene product localizes to the cytoplasm, mitochondrial lumen, extracellular region, and fungal biofilm matrix. Related genes in other species, including Fusarium oxysporum and Verticillium dahliae, are linked by sequence similarity, though these associations are not yet established for AnADH1 itself.