atrR — Aspergillus nidulans FGSC A4
Summary
ANIA_02122 (atrR) on chromosome 7 of Aspergillus nidulans FGSC A4 encodes a Zn(II)2Cys6 transcription factor of the AtrR-like family, with DNA-binding activity. The gene is associated with positive regulation of transcription by RNA polymerase II, ergosterol anabolism, biofilm formation, and hypersensitivity. Its product localises to the nucleus, cytosol, and membrane. Related genes in other species are linked to reduced virulence and pulmonary aspergillosis.
Annotations
- Chromosome
- 7
- Related genes
- atrR
- GO terms
- Hypersensitivity, Biofilm Formation, Sequence-specific DNA Binding, DNA-binding Transcription Factor Activity, RNA Polymerase II-specific, Zn binding, Nucleus, DNA Binding, DNA-dependent transcription
- Publications
- PMID:36089227, PMID:28052140, PMID:19146970, PMID:21511999, PMID:37093084, PMID:35467427, PMID:41968250, PMID:39892608
- Traits
- reduced virulence