candA-N — Aspergillus fumigatus

Summary

AFU6G10440, designated candA-N, on Aspergillus fumigatus chromosome 6 encodes a cullin-associated NEDD8-dissociated protein 1 N-terminal part TPR domain-containing protein, placing it in the CAND1/CAND2 family with ARM-type fold domains. The gene is associated with SCF complex assembly, protein breakdown, and secondary metabolism. Annotated biological process associations include sporocarp development involved in sexual reproduction, sexual sporulation resulting in formation of a cellular spore, spore germination, and sexual reproduction. The encoded product is localised to the nucleus. Studies of related genes in other species, linked by sequence similarity, further connect the family to these conserved functions.