CDA — Aspergillus fumigatus

Summary

AFU4G09940 (CDA) on chromosome 4 of Aspergillus fumigatus encodes a polysaccharide deacetylase family protein with chitin deacetylase activity, chitin binding, and zinc/metal binding. The gene is associated with chitin breakdown, chitosamine metabolism, polysaccharide breakdown, carbohydrate metabolism, fungal-type cell wall biogenesis, cell wall organization, and immune evasion. Its product localizes to the fungal-type cell wall, plasma membrane, extracellular region, and side of membrane. Studies of related genes in other species link the family to reduced virulence and unaffected pathogenicity, as well as turgor pressure, though these associations are not established for this specific gene.