LREB — Aspergillus fumigatus

Summary

AFU4G12690, symbol LREB and also known as AfLREB, AfWC-2, or GATA001 in Aspergillus fumigatus on chromosome 4, encodes a GATA transcription factor with photoreceptor activity, sequence-specific DNA binding, and zinc binding functions. It is associated with rhythmic processes, sexual reproduction, mating, and regulation of transcription by RNA polymerase II, and localises to both the cytoplasm and nucleus. The gene is linked to respiration rate. Studies of related genes in other species connect the family to reduced virulence and red light sensitivity, though these associations are not established for A. fumigatus itself.