AURZ — Aspergillus fumigatus

Summary

AFU4G14470 (symbol AURZ, also known as tpcK) in Aspergillus fumigatus encodes a protein with a dimeric alpha/beta-barrel domain and an EthD domain, possessing lyase, monooxygenase, and redox activities (EC 4.1.1.-). This gene is associated with endocrocin anabolism, secondary metabolism, the glyoxylate cycle, ethanol fermentation, and fermentation processes. It has also been linked to oxidative stress response. Studies of related genes in other species, including atrochrysone carboxylic acid decarboxylase and claH, connect the family to decarboxylation and secondary metabolite biosynthesis.