niaD — Aspergillus fumigatus

Summary

AFU5G02190 (symbol niaD) on Aspergillus fumigatus chromosome 5 encodes a putative sulfite oxidase with nitrate reductase (NADPH) activity, sulfite oxidase activity, and multiple cofactor-binding functions including moco, molybdenum ion, FAD, and heme binding. The gene is associated with nitrate assimilation, anaerobic respiration, cellular respiration, nitric oxide anabolism, siderophore anabolism, gliotoxin anabolism, ergosterol anabolism, thiamin anabolism, arginine metabolism, sulfur metabolism, polysaccharide metabolism, detoxification, metal ion transport, regeneration, homeostasis, transposition, and the mitotic cell cycle. Its product localises to mitochondria. Studies of related genes in other species link the family to nitrate uptake and molybdenum content.