lah — Aspergillus fumigatus

Summary

AFU2G08060 (lah) on chromosome 2 of Aspergillus fumigatus encodes a protein containing a Woronin anchor domain. The gene is associated with biological processes including response to wounding, alkaloid anabolism, ergot alkaloid anabolism, TOR signaling, and hypersensitivity, and its product localises to the porous cell septum. It is associated with a large network of related genes, including bbp-1, ptcB, fap1, DNJ1, mfsB, CDC2, psiT2, penM, ST3, and mug161. Studies of related genes in other species link the family to traits such as germination rate, oxidative stress response, and phosphorus concentration, as well as to cytoplasmic and apoplastic effector functions, though these associations are not yet established for this specific gene.