gtmA — Aspergillus fumigatus

Summary

AFU2G11120 (gtmA) on chromosome 2 of Aspergillus fumigatus encodes a SAM-dependent methyltransferase with thiol S-methyltransferase and hydrolase activities, belonging to the SAM-dependent methyltransferase superfamily. The gene is associated with gliotoxin anabolism, including its regulation and inhibition, as well as nonribosomal peptide anabolism, kojic acid anabolism, sulfur metabolism, secondary metabolism, detoxification, secretion, hypersensitivity, methylation, and homeostasis. It is linked to the cytoplasm. Studies of related genes in other species connect the family to additional methyltransferase and hydrolase functions, though these are not established for this species.