CDC5 — Verticillium dahliae

Summary

VdCDC5 (VDAG_10253) in Verticillium dahliae encodes a protein with a CDC5L/Cef1 domain and a Myb/SANT DNA-binding domain, and is annotated with DNA-binding molecular function. The gene is associated with mRNA splicing via the spliceosome, defense response, virus-induced PTGS, and cell growth, and its product localizes to the nucleus, cytoplasm, spliceosome, and Prp19 complex. It is associated with numerous phenotypes including abnormal cell cycle progression, increased biofilm formation, altered mating response, decreased X-ray resistance, and abnormal sporulation, as well as traits such as auxin content. Related genes in other species are linked to reduced virulence.