NOXB — Verticillium dahliae

Summary

VDAG_00032 (NOXB) in Verticillium dahliae encodes a superoxide-generating NAD(P)H oxidase, a membrane-bound enzyme that belongs to the RBOH/FRE family. The gene is associated with penetration peg formation, septin ring organization, hyphal growth, melanin anabolism, protein secretion, nitrogen utilization, and defense response, and its product localizes to the NADPH oxidase complex. Studies of related genes in other species link the NOXB family to loss of pathogenicity and reduced virulence, and the gene has been connected to verticillium wilt in related genes in other species.