CP1 — Verticillium dahliae

Summary

VdCP1 (VDAG_00116) on chromosome DS572695 of Verticillium dahliae encodes a serine carboxypeptidase (EC 3.4.16.6) belonging to the peptidase S10 and alpha/beta hydrolase families, with carboxypeptidase D activity. The gene is associated with apoptotic process, secretion, proteolysis, and methylation, and its product localises to the trans-Golgi network. Associations with numerous phenotypes have been recorded, including increased necrotic cell death and cell death, abnormal autophagy and protein secretion, altered nuclear fusion during mating, increased aneuploidy, and effects on prion inheritance, ribophagy, mitophagy, pexophagy, cytokinesis, and lifespan. The gene is also linked to chemical compound accumulation, endocytosis, and Golgi morphology. Studies of related genes in other species connect the family to apoplastic effector function.