UBI — Verticillium dahliae

Summary

VDAG_10492 (VdUBI) in Verticillium dahliae encodes a protein containing a ubiquitin-like domain and a ribosomal eS31 zinc-binding domain. The product is annotated with protein tag, mRNA binding, and structural constituent of ribosome molecular functions, and is associated with protein ubiquitination, modification-dependent proteolysis, translation, cytoplasmic translation, ribosome biogenesis, and ribosomal large subunit-nucleus export. It localises to the cytoplasm, nucleus, nucleolus, ribosome, and extracellular space. The gene is linked to numerous phenotypes including abnormal cell cycle progression, premature apoptosis, absent oxidative stress resistance, absent alkaline pH resistance, abnormal pheromone sensitivity, and altered carbon source utilisation. Studies of related genes in other species connect the family to reduced virulence and oxidative stress response.