CSN5 — Verticillium dahliae

Summary

VdCSN5 (VDAG_10288) in Verticillium dahliae encodes a metallopeptidase with deNEDDylase activity, belonging to the JAMM/MPN+ family and the COP9 signalosome (CSN) complex. It is associated with protein deneddylation and neddylation, proteolysis, secondary metabolism, mycotoxin anabolism, hyphal growth, cleistothecium development, and cell cycle modulation. The gene product localizes to the cytoplasm, cytosol, nucleus, and CSN complex. Phenotypic associations include altered shmoo formation, mating efficiency, pheromone sensitivity, cell cycle progression through G1/S and G2/M transitions, cell death, cell size, redox state, mitochondrial and peroxisomal distribution, flocculation, adhesion, and vegetative growth rate. Related genes in other species link the family to protein content traits.