BRLA — Verticillium dahliae

Summary

VDAG_06555, also known as VdBRLA, VdSTE12, VdCPH1, or VdPP-1, encodes a STE12 transcription factor containing C2H2-type zinc finger domains and is annotated with sequence-specific DNA binding and DNA binding transcription factor activity. In Verticillium dahliae, this gene is associated with mating behavior, parasexual conjugation with cellular fusion, regulation of pseudohyphal and filamentous growth, asexual reproduction and sporulation, development of symbiont in host, immune evasion, phenotypic switching, regulation of secondary metabolite biosynthesis, and pheromone response. It is also linked to verticillium wilt in lettuce, tomato, and Nicotiana benthamiana. The encoded protein localizes to the nucleus, membrane, and Tec1p-Ste12p-Dig1p and Ste12p-Dig1p-Dig2p complexes. Studies of related genes in other species link the family to sporogenesis, germination rate, and oxidative stress response.