MYO1 — Verticillium dahliae

Summary

VDAG_06810 (VdMYO1) encodes a myosin-1 motor protein with microfilament motor activity, F-actin binding, hydrolase activity and ATP binding, and contains a fungal myosin-I SH3 domain. In Verticillium dahliae, this gene is associated with cell wall modification, receptor-mediated endocytosis, actin cortical patch localization, actin filament organization, endocytosis and vesicle transport. The protein localizes to the hyphal tip, cross wall, actin cytoskeleton, endosome membrane, actin patch, cell tip, plasmalemma, cytoplasm, microvillus and myosin complex. Phenotypic associations include abnormal filamentous growth, absent spore germination, decreased endocytosis rate, delayed cytokinesis, decreased cell fusion, abnormal budding patterns, sterile phenotype, decreased necrotic cell death, abnormal prion inheritance and absent innate thermotolerance. Related genes in other species are linked to turgor pressure, potassium concentration, and both unaffected and reduced virulence.