ACLA — Verticillium dahliae

Summary

VDAG_06973 (VdACLA, ACLA) on chromosome DS572709 of Verticillium dahliae encodes a protein with ATP citrate synthase activity (EC 2.3.3.8) and succinate-CoA ligase (ADP-forming) activity, containing citrate synthase and succinyl-CoA synthase-like domains. The gene is associated with citrate and succinyl-CoA metabolism, acetyl-CoA and fatty acid anabolism, the TCA cycle, lipid metabolism, defense and immune responses, and cell death. Its product localises to the cytosol, nucleus, and succinate-CoA ligase complex. Related genes in other species are linked to loss of pathogenicity and fusarium head blight.