SOD2 — Verticillium dahliae

Summary

VDAG_07230 (SOD2, VdSOD2) encodes a manganese/iron superoxide dismutase (EC 1.15.1.1) with superoxide dismutase activity, Mn binding, and IgE binding. The enzyme localises to mitochondria, the mitochondrial lumen, and the cytosol. It is associated with removal of O2-, evasion or tolerance of host-produced AOS, detoxification, oxidative phosphorylation, morphogenesis, and homeostasis. The gene is linked to photosynthetic rate and numerous phenotypes including carbon source utilization, protein activity, chemical compound accumulation, polyploidy, anaerobic growth, fermentative growth, necrotic cell death, mating type switching, respiratory metabolism, hydrostatic pressure resistance, freeze-thaw resistance, nucleophagy, ribophagy, cell cycle progression, mitochondrial transport, pheromone sensitivity and production, radiation and alkaline pH resistance, spore wall formation, septum formation, and survival in stationary phase. Studies of related genes in other species connect the family to oxidative stress response, sodium concentration, manganese content, salt tolerance, phosphate content, and acid sensitivity.