ADH1 — Verticillium dahliae

Summary

VDAG_07507 (VdADH1, also known as ADH3, ALCC, VdALCC) encodes an alcohol dehydrogenase (EC 1.1.1.1) with aldo-keto reductase (NAD) activity and zinc binding, belonging to the ADH_Zn_CS and PKS_ER domain families. In Verticillium dahliae, this gene is associated with acetaldehyde, ethanol, and threonine breakdown, biogenic amine metabolism, RNA-directed DNA methylation, cellular response to farnesol, methylation, and homeostasis. The encoded protein is localized to the cytoplasm, mitochondrial lumen, extracellular region, and fungal biofilm matrix. VdADH1 is linked to patD and alcC, and related genes in other species are associated with primary metabolism and stress responses.