freB — Verticillium dahliae

Summary

VDAG_07588 (freB) in Verticillium dahliae encodes a ferric reductase transmembrane component 3, an oxidoreductase with NADH:Fe3+ oxidoreductase, iron chelate reductase and ferric-chelate reductase (NADPH) activities, and binds FAD and iron. The gene is associated with iron import into the cell, cellular response to iron ion starvation, iron transport and homeostasis, as well as copper ion membrane transport and copper ion import. It is also linked to filamentous growth of a unicellular organism. The product localises to the plasma membrane. Studies of related genes in other species link the family to reduced virulence and vascular wilt.