ARO2 — Verticillium dahliae

Summary

VDAG_07695 (VdARO2, ARO2) in Verticillium dahliae encodes a chorismate synthase with chorismate synthase activity (EC 4.2.3.5) and FMN reductase (NADPH) activity (EC 1.5.1.38), and belongs to the chorismate synthase family. The gene is associated with the shikimate pathway and aromatic amino acid biosynthesis, as well as amino acid biosynthesis and homeostasis. It is linked to numerous phenotypes, including increased mitochondrial rho- mutation frequency, increased mitophagy, increased chitin deposition, increased transposable element transposition, increased filamentous growth, auxotrophy, altered carbon and nitrogen source utilization, decreased respiratory growth, increased cold sensitivity, altered chronological lifespan, altered oxidative stress resistance, decreased desiccation resistance, decreased heat sensitivity, and decreased innate thermotolerance. The encoded protein localizes to both the cytosol and nucleus.