GRP2 — Verticillium dahliae

Summary

VDAG_07767 (GRP2) in Verticillium dahliae encodes a dihydroflavonol-4-reductase family protein with NADP-aldehyde reductase and lactaldehyde dehydrogenase (NADP+) activities, and is annotated to oxidoreductase activity acting on CH-OH groups. The gene is associated with terpenoid and lactate anabolism from pyruvate, as well as methylglyoxal metabolism. Its product localises to the cytoplasm, cytosol, nucleus, extracellular region, and fungal biofilm matrix. Studies of related genes in other species link the family to reduced virulence and frog-eye leaf spot disease, though these associations are not established for V. dahliae itself. The gene is also connected to the bacterial azaE gene.