ABCA — Verticillium dahliae

Summary

VDAG_08035 (VdABCA) encodes a member of the ABCG/PDR transporter family, possessing ABC-type xenobiotic transporter activity, ATP-coupled transmembrane transporter activity, and ATP hydrolase activity. The gene is associated with response to antibiotics and xenobiotic stimuli, xenobiotic detoxification by transmembrane export across the plasma membrane, cellular monoatomic cation homeostasis, and virus-induced PTGS. The product localizes to the plasma membrane. VdABCA is associated with leaf number, plant height, root length, and drought tolerance. Phenotypic associations include abnormal small molecule transport, increased sporulation rate, decreased cell death rate, and altered vacuolar distribution and transport. Related genes in other species link the family to pleiotropic drug resistance and cellular detoxification processes.