SID1 — Verticillium dahliae

Summary

VDAG_08437, designated VdSID1 and also known as VdPRK-9, encodes a protein kinase of the STE20/SPS1-PAK family on Verticillium dahliae chromosome DS572714. The product possesses MAPKKKK, protein serine/threonine kinase, and ATP-binding activities. VdSID1 is associated with induced systemic resistance, the RAM/MOR signaling network, and the cell integrity MAPK cascade. It is linked to positive regulation of the pheromone response MAPK cascade, signal transduction involved in filamentous growth, and regulation of microtubule dynamics. The protein localizes to the mitotic actomyosin contractile ring, division septum, spindle pole bodies, and the Cdc42 GTPase complex. Studies of related genes in other species link the SID1 family to reduced virulence.