PPOA — Verticillium dahliae

Summary

VdPPOA (VDAG_07521) in Verticillium dahliae encodes a haem peroxidase superfamily protein with linoleate 8R-lipoxygenase, fatty acid peroxidase, and 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase activities, along with dioxygenase and monooxygenase functions. This gene is associated with oxylipin and prostaglandin biosynthesis, positive regulation of asexual sporulation and conidia formation, and negative regulation of sexual sporulation. It is also linked to secondary metabolism, including sterigmatocystin and penicillin biosynthesis, as well as long-chain fatty acid metabolism, response to oxidative stress, and hydrogen peroxide catabolism. Studies of related genes in other species connect the PPOA family to altered virulence, including hypervirulence and reduced virulence, though these effects are not established for VdPPOA itself.