ABCA — Verticillium dahliae

Summary

VDAG_07342, designated VdABCA (also known as VdPDR5, PDR18, VdSNQ2, and other synonyms) on Verticillium dahliae chromosome DS572710, encodes an ABCG-type pleiotropic drug resistance (PDR) transporter. The product possesses ATP-coupled transmembrane transporter activity, ABC transporter function, ATP hydrolase activity, and ATP binding, and localizes to the plasma membrane. This gene is associated with xenobiotic detoxification via transmembrane export, response to antibiotics, and virus-induced post-transcriptional gene silencing. It is linked to leaf number, plant height, root length, and drought tolerance. Phenotypic associations include altered small molecule transport, increased sporulation rate, decreased cell death rate, abnormal replicative and chronological lifespan, and changes in vacuolar distribution, nutrient uptake, and cell cycle progression. Studies of related genes in other species connect the family to additional transport and stress-response processes.