CDA — Verticillium dahliae

Summary

VDAG_07142 (CDA) in Verticillium dahliae encodes a polysaccharide deacetylase family protein with chitin deacetylase activity, chitin binding, and zinc/metal binding, localized to the fungal-type cell wall, plasma membrane, and extracellular side of the membrane. This gene is associated with chitin breakdown, polysaccharide breakdown, carbohydrate metabolism, fungal-type cell wall biogenesis and organization, and immune evasion. Related genes in other species are linked to reduced virulence and effector functions, though pathogenicity is unaffected in some contexts. The gene is also associated with fungal meningitis in mouse models and has sequence similarity to genes in Verticillium nonalfalfae, Verticillium alfalfae, and various Fusarium species.