SSA1 — Verticillium dahliae

Summary

VdSSA1 (SSA1) on Verticillium dahliae chromosome DS572709 encodes an Hsp70-like protein with ATP hydrolase activity, ATP binding, heat shock protein binding, and protein folding chaperone functions, and it also acts as a transcriptional co-regulator. This gene is associated with protein acetylation, refolding, and breakdown, as well as ergosterol anabolism, cellular responses to heat, farnesol, and osmotic stress, and regulation of RNA polymerase II transcription. It localizes to the cytoplasm, nucleus, plasma membrane, fungal-type cell wall, and extracellular region. VdSSA1 is linked to increased thermotolerance, altered cell cycle progression, abnormal spore germination, premature apoptosis, increased polyploidy, and resistance to chemicals. Related genes in other species connect the family to oxidative stress response and hydrogen peroxide, protein, and phosphate content.