APS1 — Verticillium dahliae

Summary

VDAG_06801 (VdAPS1) on Verticillium dahliae chromosome DS572708 encodes a NUDIX hydrolase domain protein with diphosphoinositol-polyphosphate diphosphatase, AP5A and AP6A hydrolase, phosphodiesterase decapping endonuclease, and inositol phosphate phosphatase activities. The gene is associated with diadenosine polyphosphate metabolism, inositol phosphate and polyphosphate breakdown, and intracellular phosphate homeostasis. It has been linked to numerous phenotypes including abnormal pseudohyphal and filamentous growth, decreased sporulation and invasive growth, altered stress resistance, increased transposable element transposition, abnormal cell and organelle morphology, and changes in nutrient uptake and chemical compound accumulation. The encoded protein localises to the cytoplasm, cytosol and nucleus.