mis18 — Schizosaccharomyces pombe 972h-

Summary

SPCC970.12, also known as mis18, on chromosome 3 of Schizosaccharomyces pombe 972h-, encodes a zinc-binding protein belonging to the Mis18 and Yippee/Mis18/Cereblon protein families. The gene is associated with fundamental cell cycle processes, including mitosis, interphase, anaphase, telophase, and S phase, as well as cell division and chromosome division. It has been linked to centromere clustering, centromere localization, kinetochore assembly, and CENP-A containing chromatin assembly. The encoded product localizes to the centromere complex, kinetochore, chromatin, cytoplasm, and nucleus, and is also associated with the CENP-A recruiting complex.