tas3 — Schizosaccharomyces pombe 972h-

Summary

SPBC83.03C (tas3) on chromosome 2 of Schizosaccharomyces pombe encodes a protein that belongs to the Tas3_C domain family and binds siRNA. It is a component of the RITS complex and is associated with RNAi-mediated heterochromatin assembly at centromeres, centromeric silencing, and silencing of the silent mating-type cassette and telomeres. The gene is associated with chromatin silencing, mating, chromosome division, and methylation. The protein localises to the nucleus, subtelomeric heterochromatin, heterochromatin, mating-type region heterochromatin, the spindle pole body (SPB), and centric heterochromatin.