ndc80 — Schizosaccharomyces pombe 972h-

Summary

SPBC11C11.03, also known as ndc80 in Schizosaccharomyces pombe 972h- on chromosome 2, encodes a protein of the Ndc80 family. The product possesses kinetochore adaptor activity and microtubule binding, and localizes to the Ndc80 complex, outer kinetochore, and microtubule organizing center. It is associated with mitotic and meiotic chromosome segregation, spindle attachment and elongation, centromere clustering and localization, microtubule dynamics and shortening, kinetochore assembly, spindle assembly checkpoint, and interphase and prophase processes. Studies of related genes in other species link it to similar kinetochore functions.