poz1 — Schizosaccharomyces pombe 972h-

Summary

SPAC19G12.13C (poz1) on chromosome 1 of Schizosaccharomyces pombe encodes a protein with DNA-binding activity. The gene is associated with telomere biology, including telomere maintenance, telomere capping, telomere organization, and telomere maintenance via telomere lengthening. It is also linked to the regulation of DNA replication, homologous recombination, and cell cycle modulation, including interphase and S phase. Additional associations include chromatin and centromeric silencing, telomeric silencing, the DNA damage checkpoint, meiosis, mating, and spore formation. The protein localizes to the nucleus, cytosol, and the telomeric repeat region of chromosomes. Studies of related genes in other species have linked the family to the telosome complex.