CDC24 — Saccharomyces cerevisiae S288c

Summary

YAL041W (SCD1/CDC24) in Saccharomyces cerevisiae S288c is annotated with lipid binding and GDS (guanine nucleotide dissociation stimulator) molecular functions, and contains DH, PH, PB1, and CH domains. The gene is associated with asymmetric cell division, cell polarization, polar cell growth, karyogamy, pheromone response, exocytosis, regulation of mitotic spindle organization, chitin anabolism, and the stringent response. It localizes to the site of polarized growth, cell tip, mating projection tip, cleavage furrow, and division septum. Phenotypic associations include absent budding and shmoo formation, decreased axial budding pattern, abnormal mating projection morphology, cell cycle arrest, decreased mating efficiency and sporulation, altered cell size, increased chitin deposition, and decreased viability and hyperosmotic stress resistance. Studies of related genes in other species link it to the Cdc42 GTPase complex.