SNC1 — Saccharomyces cerevisiae S288c

Summary

YAL030W, also known as SNC1 in Saccharomyces cerevisiae S288c, encodes a V-SNARE protein with syntaxin-binding activity that is a core component of the SNARE complex. This gene is associated with vesicle-mediated trafficking processes including endosomal transport, post-Golgi transport, endocytosis, endocytic recycling, vesicle docking, tethering and targeting, as well as SNARE complex assembly. It has been linked to constitutive exocytosis, protein palmitoylation, ER inheritance, mitochondrial inner membrane protein import, spore wall assembly, meiosis, and sporogenesis. Localization evidence links the product to the SNARE complex, endosome, Golgi complex, plasma membrane, cell division site, and meiotic spindle pole. Phenotypic associations include abnormal budding index, cell cycle progression, actin cytoskeleton morphology, and nuclear morphology, along with decreased endocytosis, filamentous growth, and vegetative growth, increased cell size, and altered chemical resistance and competitive fitness.