SSD1 — Neurospora crassa

Summary

NCU01197 (SSD1, also known as gul-1) on Neurospora crassa chromosome 5 encodes a protein with Dis3l2_C, Dis3_CSD2, RNR Ribonuclease, RNase_II/R, and NA-bd_OB-fold domains, and is associated with RNA exonuclease activity, mRNA 5'-UTR binding, mRNA regulatory element binding translation repressor activity, RNA nuclease activity, 3'-5' exoribonuclease activity, RNA endonuclease activity, endonuclease activity, poly(U) binding, mRNA 3'-UTR binding, small GTPase binding, identical protein binding, RNA binding, and metal binding. The protein localises to the Mmi1 nuclear focus, cytoplasmic exosome (RNase complex), exosome (RNase complex), nuclear exosome (RNase complex), P body, stress granule, cellular bud neck, nucleoplasm, nucleolus, and chromatin. SSD1 is associated with regulation of G1/G0 transition, exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript, nuclear RNA surveillance, nuclear mRNA surveillance of mRNA 3'-end processing, termination of RNA polymerase II transcription (exosome-dependent), polyuridylation-dependent mRNA catabolic process, intracellular mRNA localization, rRNA breakdown, nuclear polyadenylation-dependent mRNA catabolic process, exonucleolytic trimming to generate mature 3