FLBD — Neurospora crassa

Summary

NCU01312 (FLBD, rca-1) in Neurospora crassa chromosome 5 encodes a Myb-1 protein with a Myb domain and SANT/Myb DNA-binding motif. The product is a transcription factor that binds RNA polymerase II and III cis-regulatory regions and is associated with the SNAPc complex, nucleus, and membrane. This gene is associated with regulation of DNA re-duplication, cell cycle G1/S phase transition, stomatal complex patterning, snRNA transcription, conidiophore development, ascospore formation, hyphal growth, sporulation, calcium signaling, sphingolipid anabolism, signal transduction, and positive regulation of RNA polymerase II transcription. It is also linked to multicellular organismal water homeostasis, activation of salinity response, response to lipid, and upregulation of response to thirst. Related genes in other species link the family to germination rate and oxidative stress response.