PSD2 — Magnaporthe oryzae 70-15

Summary

MGG_07037 (MoPSD2, PSD2) on chromosome 2 of Magnaporthe oryzae 70-15 encodes a protein with a PSD_type2_pro domain, a PSD domain, a PS_Dcarbxylase domain, a C2 domain, and EF-hand calcium-binding motifs. The protein is annotated with phosphatidylserine decarboxylase activity (EC 4.1.1.65) and L-tryptophan decarboxylase activity, binds phospholipids and calcium ions, and localises to the Golgi stack, endosome membrane, fungal-type vacuole membrane, mitochondria, cytosol, and cell division site. MoPSD2 is associated with phosphatidylethanolamine, phosphatidylcholine, and phosphatidylserine anabolism, the Kennedy pathway, phosphoglyceride metabolism, protein autoprocessing, autophagy, methylation, and filamentous growth in response to chemical, starvation, and biotic stimuli. Phenotypic associations include decreased colony size, abnormal pseudohyphal growth, cytokinesis defects, altered apoptosis rates, decreased oxidative phosphorylation, mitochondrial transport and genome maintenance defects, and aberrant peroxisomal and vacuolar transport.